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[DOI] [PubMed] [Google Scholar] 231.Gottsch M.L., Cunningham M.J., Smith J.T., Popa S.M., Acohido B.V., Crowley W.F., Seminara S., Clifton D.K., Steiner R.A

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Essentially, the shared pathogenic core of the pathogenesis of NP and NPP lies in peripheral and/or) central sensitization following repeated and persistent exposure to non-harmful stimuli—that is, a separation of central (or peripheral) sensitization occurring without significant activation of nociceptors or clear evidence of nerve damage of patients ( Figure 5 )